Spider-Girl is an alternate version of Jessica Drew from the Ultimate Marvel universe. Unlike her original version, this Jessica is in fact an altered, artificially aged female clone of Spider-Man, aka Peter Parker, created by Doctor Octopus, and thus has his memories and shades of his personality. Unlike Peter, she has the ability to create organic webbing from her finger tips, but has all of his other abilities. She is a member of S.H.I.E.L.D., and a mentor and best friend to Miles Morales, the second Spider-Man.
- Despite being named Spider-Girl, her costume resembles the one formerly worn by the Spider-Woman from Miles Morales' universe before she took on the Black Widow title. Additionally, her official Lego.com description describes her as "Petra Parker" from the Ultimate Spider-Man TV series despite lacking any resemblance.