Porpentina Esther 'Tina' Goldstein was born somewhere in the United States during the late 19th Century and it may be possible that she learned magic at Ilvermorny School of Witchcraft and Wizardry. She also has a younger sister named Queenie. It has also hinted that they were orphaned by the deaths of their parents early on, as they were described to 'have raised each other' afterwards, which later explains their strong bonds in adulthood.
Later on, she started working for the Magical Congress of the United States of America as an Auror, but because she stood up for a hapless individual her superiors looked down upon, she was demoted far below her abilities.
In 1926, she later met British magizoologist Newt Scamander during his trip to the United States as a part of his international expedition to uncover magical species. They eventually married and she moved to the United Kingdom with him in an undetermined time, as well as giving birth to at least one child who became the parent of Rolf Scamander. As of the late 20th century, she and Newt live in Dorest with three pet Kneazles: Hoppy, Milly, and Mauler. Upon Rolf's marriage to Luna Lovegood, she and Newt became great-grandparents to their twin boys Lysander and Lorcan.